Paradoxical role of reactive oxygen species in bone remodelling: implications in osteoporosis and possible nanotherapeutic interventions
Osteoporosis is a metabolic bone disorder that affects both sexes and is the most common jumbo wind gold cause of fractures.Osteoporosis therapies primarily inhibit osteoclast activity, and are seldom designed to trigger new bone growth thereby frequently causing severe systemic adverse effects.Physiologically, the intracellular redox state depends